Open Reading Frame 50 Protein of Kaposi's Sarcoma-Associated Herpesvirus Directly Activates the Viral PAN and K12 Genes by Binding to Related Response Elements

Open reading frame (ORF) 50 protein is capable of activating the entire lytic cycle of Kaposi's sarcoma-associated herpesvirus (KSHV), but its mechanism of action is not well characterized. Here we demonstrate that ORF 50 protein activates two KSHV lytic cycle genes, PAN (polyadenylated nuclear RNA)...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Chang, Pey-Jium, Shedd, Duane, Gradoville, Lyn, Cho, Myung-Sam, Chen, Lee-Wen, Chang, Jimmy, Miller, George
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2002
Fag:	Virus-Cell Interactions
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136055/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11884541/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.7.3168-3178.2002
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