Crystal structure of a core spliceosomal protein interface

The precise excision of introns from precursor mRNAs (pre-mRNAs) in eukaryotes is accomplished by the spliceosome, a complex assembly containing five small nuclear ribonucleoprotein (snRNP) particles. Human p14, a component of the spliceosomal U2 and U11/U12 snRNPs, has been shown to associate direc...

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Autori principali: Schellenberg, Matthew J., Edwards, Ross A., Ritchie, Dustin B., Kent, Oliver A., Golas, Monika M., Stark, Holger, Lührmann, Reinhard, Glover, J. N. Mark, MacMillan, Andrew M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360545/
https://ncbi.nlm.nih.gov/pubmed/16432215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508048103
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