Capsid Protein C of Tick-Borne Encephalitis Virus Tolerates Large Internal Deletions and Is a Favorable Target for Attenuation of Virulence

Deletions ranging in size from 4 to 21 amino acid residues were introduced into the capsid protein of the flavivirus tick-borne encephalitis (TBE) virus. These deletions incrementally affected a hydrophobic domain which is present at the center of all flavivirus capsid protein sequences and part of...

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Hlavní autoři: Kofler, Regina M., Heinz, Franz X., Mandl, Christian W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC136049/
https://ncbi.nlm.nih.gov/pubmed/11884577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.7.3534-3543.2002
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