Inhibition of Hepatitis B Virus Replication by Interferon Requires Proteasome Activity†

Hepatitis B virus (HBV) replication is inhibited in a noncytopathic manner by alpha/beta interferon (IFN-α/β) and IFN-γ. We demonstrate here that inhibitors of cellular proteasome activity can block this antiviral effect. These results suggest that a critical component of the IFN-induced antiviral r...

Full description

Saved in:
Bibliographic Details
Main Authors: Robek, Michael D., Wieland, Stefan F., Chisari, Francis V.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC136040/
https://ncbi.nlm.nih.gov/pubmed/11884582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.7.3570-3574.2002
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items