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Flagellin Is an Effective Adjuvant for Immunization against Lethal Respiratory Challenge with Yersinia pestis

Gram-negative flagellin, a Toll-like receptor 5 (TLR5) agonist, is a potent inducer of innate immune effectors such as cytokines and nitric oxide. In the lung, flagellin induces a localized and transient innate immune response characterized by neutrophil infiltration and the production of cytokines...

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Detalhes bibliográficos
Main Authors: Honko, Anna N., Sriranganathan, Nammalwar, Lees, Cynthia J., Mizel, Steven B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360354/
https://ncbi.nlm.nih.gov/pubmed/16428759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.2.1113-1120.2006
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