Role of AFR1, an ABC Transporter-Encoding Gene, in the In Vivo Response to Fluconazole and Virulence of Cryptococcus neoformans

We have recently demonstrated that upregulation of the ATP binding cassette (ABC) transporter-encoding gene AFR1 in Cryptococcus neoformans is involved in the in vitro resistance to fluconazole of this yeast. In the present study, we investigated the role of AFR1 in the in vivo response to fluconazo...

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Bibliografische gegevens
Hoofdauteurs: Sanguinetti, Maurizio, Posteraro, Brunella, La Sorda, Marilena, Torelli, Riccardo, Fiori, Barbara, Santangelo, Rosaria, Delogu, Giovanni, Fadda, Giovanni
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2006
Onderwerpen:
Fungal and Parasitic Infections
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360305/
https://ncbi.nlm.nih.gov/pubmed/16428784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.2.1352-1359.2006
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