Role of AFR1, an ABC Transporter-Encoding Gene, in the In Vivo Response to Fluconazole and Virulence of Cryptococcus neoformans

We have recently demonstrated that upregulation of the ATP binding cassette (ABC) transporter-encoding gene AFR1 in Cryptococcus neoformans is involved in the in vitro resistance to fluconazole of this yeast. In the present study, we investigated the role of AFR1 in the in vivo response to fluconazo...

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Detalhes bibliográficos
Main Authors: Sanguinetti, Maurizio, Posteraro, Brunella, La Sorda, Marilena, Torelli, Riccardo, Fiori, Barbara, Santangelo, Rosaria, Delogu, Giovanni, Fadda, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360305/
https://ncbi.nlm.nih.gov/pubmed/16428784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.2.1352-1359.2006
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