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In Adenovirus Type 12 Tumorigenic Cells, Major Histocompatibility Complex Class I Transcription Shutoff Is Overcome by Induction of NF-κB and Relief of COUP-TFII Repression

The surface levels of major histocompatibility complex class I antigens are diminished on tumorigenic adenovirus type 12 (Ad12)-transformed cells, enabling them to escape from immunosurveillant cytotoxic T lymphocytes (CTLs). This is due to the down-regulation of the class I transcriptional enhancer...

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Pubblicato in:J Virol
Autori principali: Hou, Shihe, Guan, Hancheng, Ricciardi, Robert P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2002
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136028/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11884545/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.7.3212-3220.2002
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