In Adenovirus Type 12 Tumorigenic Cells, Major Histocompatibility Complex Class I Transcription Shutoff Is Overcome by Induction of NF-κB and Relief of COUP-TFII Repression

The surface levels of major histocompatibility complex class I antigens are diminished on tumorigenic adenovirus type 12 (Ad12)-transformed cells, enabling them to escape from immunosurveillant cytotoxic T lymphocytes (CTLs). This is due to the down-regulation of the class I transcriptional enhancer...

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Bibliographic Details
Main Authors: Hou, Shihe, Guan, Hancheng, Ricciardi, Robert P.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC136028/
https://ncbi.nlm.nih.gov/pubmed/11884545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.7.3212-3220.2002
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