Coxsackievirus B3 Replication Is Reduced by Inhibition of the Extracellular Signal-Regulated Kinase (ERK) Signaling Pathway

Coxsackievirus B3 (CVB3) is the most common human pathogen for viral myocarditis. We have previously shown that the signaling protein p21(ras) GTPase-activating protein (RasGAP) is cleaved and that mitogen-activated protein kinases (MAPKs) ERK1/2 are activated in the late phase of CVB3 infection. Ho...

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Autors principals: Luo, Honglin, Yanagawa, Bobby, Zhang, Jingchun, Luo, Zongshu, Zhang, Mary, Esfandiarei, Mitra, Carthy, Christopher, Wilson, Janet E., Yang, Decheng, McManus, Bruce M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC136021/
https://ncbi.nlm.nih.gov/pubmed/11884562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.7.3365-3373.2002
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