Lipopolysaccharide Sequestrants: Structural Correlates of Activity and Toxicity in Novel Acylhomospermines

Lipopolysaccharides (LPS), otherwise termed ‘endotoxins’, are outer-membrane constituents of Gram-negative bacteria. Lipopolysaccharides play a key role in the pathogenesis of ‘Septic Shock’, a major cause of mortality in the critically ill patient. Therapeutic options aimed at limiting downstream s...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Miller, Kelly A., Kumar, E.V.K. Suresh, Wood, Stewart J., Cromer, Jens R., Datta, Apurba, David*, Sunil A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2005
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360202/
https://ncbi.nlm.nih.gov/pubmed/15801849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm049449j
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