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Selective Targeting and Inducible Destruction of Human Cancer Cells by Retroviruses with Envelope Proteins Bearing Short Peptide Ligands

In the accompanying study, we show how retroviral tropism can be redirected by insertion of short peptide ligands at multiple locations in envelope. Here we use this approach to selectively target and destroy human cancer cells. Many cancer cells overexpress specific cell surface receptors. We have...

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Main Authors: Gollan, Timothy J., Green, Michael R.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2002
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC136017/
https://ncbi.nlm.nih.gov/pubmed/11884581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.7.3564-3569.2002
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