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Factors affecting the direct targeting of murine leukemia virus vectors containing peptide ligands in the envelope protein

To develop a reliable strategy for cell-specific delivery of retroviral vectors, we genetically modified the envelope (Env) protein of the ecotropic Moloney murine leukemia virus. We found a site in the variable region A, where the insertion of ligands, epidermal growth factor (EGF) and stromal-deri...

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Autores principales: Katane, Masumi, Takao, Eiko, Kubo, Yoshinao, Fujita, Rika, Amanuma, Hiroshi
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084232/
https://ncbi.nlm.nih.gov/pubmed/12189179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf179
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