Viable Human Cytomegalovirus Recombinant Virus with an Internal Deletion of the IE2 86 Gene Affects Late Stages of Viral Replication

Using bacterial artificial chromosome (BAC) technology, we have constructed and characterized a human cytomegalovirus recombinant virus with a mutation in the exon specific for the major immediate-early region 2 (IE2) gene product. The resulting IE2 86-kDa protein (IE2 86) has an internal deletion o...

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Bibliographic Details
Main Authors: Sanchez, Veronica, Clark, Charles L., Yen, Judy Y., Dwarakanath, Roopashree, Spector, Deborah H.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC135995/
https://ncbi.nlm.nih.gov/pubmed/11861863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.6.2973-2989.2002
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