Viable Human Cytomegalovirus Recombinant Virus with an Internal Deletion of the IE2 86 Gene Affects Late Stages of Viral Replication

Using bacterial artificial chromosome (BAC) technology, we have constructed and characterized a human cytomegalovirus recombinant virus with a mutation in the exon specific for the major immediate-early region 2 (IE2) gene product. The resulting IE2 86-kDa protein (IE2 86) has an internal deletion o...

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Detalhes bibliográficos
Main Authors: Sanchez, Veronica, Clark, Charles L., Yen, Judy Y., Dwarakanath, Roopashree, Spector, Deborah H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC135995/
https://ncbi.nlm.nih.gov/pubmed/11861863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.6.2973-2989.2002
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