CD4 Independence of Simian Immunodeficiency Virus Envs Is Associated with Macrophage Tropism, Neutralization Sensitivity, and Attenuated Pathogenicity

To investigate the basis for envelope (Env) determinants influencing simian immunodeficiency virus (SIV) tropism, we studied a number of Envs that are closely related to that of SIVmac239, a pathogenic, T-tropic virus that is neutralization resistant. The Envs from macrophage-tropic (M-tropic) virus...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Puffer, Bridget A., Pöhlmann, Stefan, Edinger, Aimee L., Carlin, Dan, Sanchez, Melissa D., Reitter, Julie, Watry, Debbie D., Fox, Howard S., Desrosiers, Ronald C., Doms, Robert W.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2002
विषय:
Virus-Cell Interactions
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC135960/
https://ncbi.nlm.nih.gov/pubmed/11861825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.6.2595-2605.2002
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