Antibody-Mediated Enhancement of Human Immunodeficiency Virus Type 1 Infectivity Is Determined by the Structure of gp120 and Depends on Modulation of the gp120-CCR5 Interaction

In this study, we characterized the viral determinants of coreceptor usage in relation to susceptibility to antibody-mediated neutralization or enhancement of infectivity by using chimeras of three highly related human immunodeficiency virus type 1 (HIV-1) isolates of different phenotypes. We found...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Guillon, Christophe, Schutten, Martin, Boers, Patrick H. M., Gruters, Rob A., Osterhaus, Albert D. M. E.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135957/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11861850/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.6.2827-2834.2002
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