High-Throughput Selection of Retrovirus Producer Cell Lines Leads to Markedly Improved Efficiency of Germ Line-Transmissible Insertions in Zebra Fish

Vesicular stomatitis virus glycoprotein G-pseudotyped mouse retroviral vectors have been used as mutagens for a large-scale insertional mutagenesis screen in the zebra fish. To reproducibly generate high-titer virus stocks, we devised a method for rapidly selecting cell lines that can yield high-tit...

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Vydáno v:	J Virol
Hlavní autoři:	Chen, Wenbiao, Burgess, Shawn, Golling, Greg, Amsterdam, Adam, Hopkins, Nancy
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2002
Témata:	Gene Therapy
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135931/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11836396/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.76.5.2192-2198.2002
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