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Herpes Simplex Virus ICP0 and ICP34.5 Counteract Distinct Interferon-Induced Barriers to Virus Replication

Interferon inhibits virus replication through multiple mechanisms. Here we show that herpes simplex virus proteins ICP0 and ICP34.5 overcome interferon-induced barriers to viral transcription and translation, respectively. These cytokine-induced antiviral mechanisms are differentially expressed in e...

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Bibliographic Details
Published in:J Virol
Main Authors: Mossman, Karen L., Smiley, James R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2002
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135894/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11799195/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.4.1995-1998.2002
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