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Segregation of CD4 and CXCR4 into Distinct Lipid Microdomains in T Lymphocytes Suggests a Mechanism for Membrane Destabilization by Human Immunodeficiency Virus

Recent evidence has suggested that plasma membrane sphingolipids and cholesterol spontaneously coalesce into raft-like microdomains and that specific proteins, including CD4 and some other T-cell signaling molecules, sequester into these rafts. In agreement with these results, we found that CD4 and...

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Bibliografiska uppgifter
Huvudupphovsmän: Kozak, Susan L., Heard, Jean Michel, Kabat, David
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2002
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC135872/
https://ncbi.nlm.nih.gov/pubmed/11799176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.4.1802-1815.2002
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