Segregation of CD4 and CXCR4 into Distinct Lipid Microdomains in T Lymphocytes Suggests a Mechanism for Membrane Destabilization by Human Immunodeficiency Virus

Recent evidence has suggested that plasma membrane sphingolipids and cholesterol spontaneously coalesce into raft-like microdomains and that specific proteins, including CD4 and some other T-cell signaling molecules, sequester into these rafts. In agreement with these results, we found that CD4 and...

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Pubblicato in:	J Virol
Autori principali:	Kozak, Susan L., Heard, Jean Michel, Kabat, David
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Virus-Cell Interactions
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135872/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11799176/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.4.1802-1815.2002
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