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Adenovirus E1A N-Terminal Amino Acid Sequence Requirements for Repression of Transcription In Vitro and In Vivo Correlate with Those Required for E1A Interference with TBP-TATA Complex Formation

The adenovirus (Ad) E1A 243R oncoprotein encodes an N-terminal transcription repression domain that is essential for early viral functions, cell immortalization, and cell transformation. The transcription repression function requires sequences within amino acids 1 to 30 and 48 to 60. To elucidate th...

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Detalhes bibliográficos
Main Authors: Boyd, Janice M., Loewenstein, Paul M., Tang, Qing-quan, Yu, Li, Green, Maurice
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC135854/
https://ncbi.nlm.nih.gov/pubmed/11773419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.3.1461-1474.2002
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