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(1)H NMR determination of base-pair lifetimes in oligonucleotides containing single base mismatches

Proton nuclear magnetic resonance (NMR) spectroscopy is employed to characterize the kinetics of base-pair opening in a series of 9mer duplexes containing different single base mismatches. The imino protons from the different mismatched, as well as fully matched, duplexes are assigned from the imino...

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Detalhes bibliográficos
Main Authors: Bhattacharya, Pratip K., Cha, Julie, Barton, Jacqueline K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC135820/
https://ncbi.nlm.nih.gov/pubmed/12409465
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