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Rapid parallel mutation scanning of gene fragments using a microelectronic protein–DNA chip format

We have developed a method for the de novo discovery of genetic variations, including single nucleotide polymorphisms and mutations, on microelectronic chip devices. The method combines the features of electronically controlled DNA hybridisation on open-format microarrays, with mutation detection by...

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Main Authors: Behrensdorf, Heike A., Pignot, Marc, Windhab, Norbert, Kappel, Andreas
格式: Artigo
語言:Inglês
出版: Oxford University Press 2002
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC135765/
https://ncbi.nlm.nih.gov/pubmed/12136112
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