The effect of ICAD-S on the formation and intracellular distribution of a nucleolytically active caspase-activated DNase

We show here that co-expression of murine CAD with either ICAD-L or ICAD-S in Escherichia coli as well as mammalian cells leads to a functional DFF complex, which after caspase-3 activation releases a nucleolytically active DNase. The chaperone activity of ICAD-S is between one and two orders of mag...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Scholz, Sebastian Richard, Korn, Christian, Gimadutdinow, Oleg, Knoblauch, Michael, Pingoud, Alfred, Meiss, Gregor
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 2002
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135751/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12136086/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf431
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