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Rapid and Irreversible CD4(+) T-Cell Depletion Induced by the Highly Pathogenic Simian/Human Immunodeficiency Virus SHIV(DH12R) Is Systemic and Synchronous

Highly pathogenic simian/human immunodeficiency virus chimeric viruses are known to induce a rapid, irreversible depletion of CD4(+) T lymphocytes in the peripheral blood of acutely infected macaque monkeys. To more fully assess the systemic effects of this primary virus infection, specimens were co...

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Detalhes bibliográficos
Main Authors: Igarashi, Tatsuhiko, Brown, Charles R., Byrum, Russell A., Nishimura, Yoshiaki, Endo, Yasuyuki, Plishka, Ronald J., Buckler, Charles, Buckler-White, Alicia, Miller, Georgina, Hirsch, Vanessa M., Martin, Malcolm A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC135728/
https://ncbi.nlm.nih.gov/pubmed/11739702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.1.379-391.2002
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