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The C-Terminal 88 Amino Acids of the Sendai Virus P Protein Have Multiple Functions Separable by Mutation

The Sendai virus P-L polymerase complex binds the NP-encapsidated nucleocapsid (NC) template through a P-NP interaction. To identify P amino acids responsible for binding we performed site-directed mutagenesis on the C-terminal 88 amino acids in the NC binding domain. The mutant P proteins expressed...

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Udgivet i:J Virol
Principais autores: Tuckis, Jeffery, Smallwood, Sherin, Feller, Joyce A., Moyer, Sue A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2002
Fag:
Replication
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135727/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11739672/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.1.68-77.2002
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