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“Rule of Six”: How Does the Sendai Virus RNA Polymerase Keep Count?
The “rule of six” stipulates that the Paramyxovirus RNA polymerase efficiently replicates only viral genomes counting 6n + 0 nucleotides. Because the nucleocapsid proteins (N) interact with 6 nucleotides, an exact nucleotide-N match at the RNA 3′-OH end (3′-OH congruence) may be required for recogni...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2001
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC114204/ https://ncbi.nlm.nih.gov/pubmed/11312321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.10.4506-4518.2001 |
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