Reverse Genetics Demonstrates that Proteolytic Processing of the Ebola Virus Glycoprotein Is Not Essential for Replication in Cell Culture

Ebola virus, a prime example of an emerging pathogen, causes fatal hemorrhagic fever in humans and in nonhuman primates. Identification of major determinants of Ebola virus pathogenicity has been hampered by the lack of effective strategies for experimental mutagenesis. Here we exploit a reverse gen...

Полное описание

Библиографические подробности

Опубликовано в::	J Virol
Главные авторы:	Neumann, Gabriele, Feldmann, Heinz, Watanabe, Shinji, Lukashevich, Igor, Kawaoka, Yoshihiro
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 2002
Предметы:	Virus-Cell Interactions
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135697/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11739705/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.1.406-410.2002
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