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Late Activation of Stress Kinases (SAPK/JNK) by Genotoxins Requires the DNA Repair Proteins DNA-PK(cs) and CSB

Although genotoxic agents are powerful inducers of stress kinases (SAPK/JNK), the contribution of DNA damage itself to this response is unknown. Therefore, SAPK/JNK activation of cells harboring specific defects in DNA damage-recognition mechanisms was studied. Dual phosphorylation of SAPK/JNK by th...

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Main Authors: Fritz, Gerhard, Kaina, Bernd
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356594/
https://ncbi.nlm.nih.gov/pubmed/16319174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-07-0606
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