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Brd4 Is Required for Recovery from Antimicrotubule Drug-induced Mitotic Arrest: Preservation of Acetylated Chromatin

The mammalian bromodomain protein Brd4 interacts with mitotic chromosomes by binding to acetylated histone H3 and H4 and is thought to play a role in epigenetic memory. Mitotic cells are susceptible to antimicrotubule drugs. These drugs activate multiple response pathways and arrest cells at mitosis...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Nishiyama, Akira, Dey, Anup, Miyazaki, Jun-ichi, Ozato, Keiko
פורמט: Artigo
שפה:Inglês
יצא לאור: The American Society for Cell Biology 2006
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356591/
https://ncbi.nlm.nih.gov/pubmed/16339075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-08-0729
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