Targeting of Protein Kinase C-ε during Fcγ Receptor-dependent Phagocytosis Requires the εC1B Domain and Phospholipase C-γ1

Protein kinase C-ε (PKC-ε) translocates to phagosomes and promotes uptake of IgG-opsonized targets. To identify the regions responsible for this concentration, green fluorescent protein (GFP)-protein kinase C-ε mutants were tracked during phagocytosis and in response to exogenous lipids. Deletion of...

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Auteurs principaux: Cheeseman, Keylon L., Ueyama, Takehiko, Michaud, Tanya M., Kashiwagi, Kaori, Wang, Demin, Flax, Lindsay A., Shirai, Yasuhito, Loegering, Daniel J., Saito, Naoaki, Lennartz, Michelle R.
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2006
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356590/
https://ncbi.nlm.nih.gov/pubmed/16319178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-12-1100
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