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G Protein-coupled Receptor Gpr4 Senses Amino Acids and Activates the cAMP-PKA Pathway in Cryptococcus neoformans

The Gα protein Gpa1 governs the cAMP-PKA signaling pathway and plays a central role in virulence and differentiation in the human fungal pathogen Cryptococcus neoformans, but the signals and receptors that trigger this pathway were unknown. We identified seven putative proteins that share identity w...

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Detalhes bibliográficos
Principais autores: Xue, Chaoyang, Bahn, Yong-Sun, Cox, Gary M., Heitman, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356578/
https://ncbi.nlm.nih.gov/pubmed/16291861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-07-0699
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