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A comprehensive continuous-time model for the appearance of CGH signal due to chromosomal missegregations during mitosis

Aneuploidy, the gain or loss of large regions of the genome, is a common feature in cancer cells. Irregularities in chromosomal copy number caused by missegregations of chromosomes during mitosis can be visualized by cytogenetic techniques including fluorescence in situ hybridization (FISH), spectra...

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Main Authors: Desper, Richard, Difilippantonio, Michael J., Ried, Thomas, Schäffer, Alejandro A.
Formato: Artigo
Idioma:Inglês
Publicado: 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356526/
https://ncbi.nlm.nih.gov/pubmed/16043196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mbs.2005.05.005
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