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Utilizing α-Fetoprotein Expression to Enhance Oncolytic Viral Therapy in Hepatocellular Carcinoma
OBJECTIVE: To determine whether α-fetoprotein (AFP)-regulated ribonucleotide reductase (RR) production would promote more vigorous and specific viral killing in AFP-expressing hepatocellular carcinoma (HCC). BACKGROUND: AFP is expressed in over 70% of primary HCC but not in normal adult liver. AFP p...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1356467/ https://ncbi.nlm.nih.gov/pubmed/15383793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.sla.0000141197.57930.7a |
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