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Utilizing Tumor Hypoxia to Enhance Oncolytic Viral Therapy in Colorectal Metastases
OBJECTIVE: To determine the effects of hypoxia-induced ribonucleotide reductase (RR) production on herpes oncolytic viral therapy. SUMMARY BACKGROUND DATA: Hypoxia is a common tumor condition correlated with therapeutic resistance and metastases. Attenuated viruses offer a unique cancer treatment by...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1356298/ https://ncbi.nlm.nih.gov/pubmed/15166969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.sla.0000128308.36393.38 |
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