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3-D structural and functional characterization of the purified K(ATP) channel complex Kir6.2–SUR1

ATP-sensitive potassium (K(ATP)) channels conduct potassium ions across cell membranes and thereby couple cellular energy metabolism to membrane electrical activity. Here, we report the heterologous expression and purification of a functionally active K(ATP) channel complex composed of pore-forming...

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Detalhes bibliográficos
Main Authors: Mikhailov, Michael V, Campbell, Jeff D, de Wet, Heidi, Shimomura, Kenju, Zadek, Brittany, Collins, Richard F, Sansom, Mark S P, Ford, Robert C, Ashcroft, Frances M
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356316/
https://ncbi.nlm.nih.gov/pubmed/16308567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600877
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