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Peroxisomal Targeting Signal Receptor Pex5p Interacts with Cargoes and Import Machinery Components in a Spatiotemporally Differentiated Manner: Conserved Pex5p WXXXF/Y Motifs Are Critical for Matrix Protein Import

Two isoforms of the peroxisomal targeting signal type 1 (PTS1) receptor, termed Pex5pS and (37-amino-acid-longer) Pex5pL, are expressed in mammals. Pex5pL transports PTS1 proteins and Pex7p-PTS2 cargo complexes to the initial Pex5p-docking site, Pex14p, on peroxisome membranes, while Pex5pS transloc...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Principais autores: Otera, Hidenori, Setoguchi, Kiyoko, Hamasaki, Maho, Kumashiro, Toshitaka, Shimizu, Nobuhiro, Fujiki, Yukio
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2002
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135613/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11865044/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.6.1639-1655.2002
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