Peroxisomal Targeting Signal Receptor Pex5p Interacts with Cargoes and Import Machinery Components in a Spatiotemporally Differentiated Manner: Conserved Pex5p WXXXF/Y Motifs Are Critical for Matrix Protein Import

Two isoforms of the peroxisomal targeting signal type 1 (PTS1) receptor, termed Pex5pS and (37-amino-acid-longer) Pex5pL, are expressed in mammals. Pex5pL transports PTS1 proteins and Pex7p-PTS2 cargo complexes to the initial Pex5p-docking site, Pex14p, on peroxisome membranes, while Pex5pS transloc...

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Bibliographische Detailangaben
Hauptverfasser: Otera, Hidenori, Setoguchi, Kiyoko, Hamasaki, Maho, Kumashiro, Toshitaka, Shimizu, Nobuhiro, Fujiki, Yukio
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Cell and Organelle Structure and Assembly
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC135613/
https://ncbi.nlm.nih.gov/pubmed/11865044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.6.1639-1655.2002
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