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Tandem chimerism as a means to increase protein complexity in the human genome

The “one-gene, one-protein” rule, coined by Beadle and Tatum, has been fundamental to molecular biology. The rule implies that the genetic complexity of an organism depends essentially on its gene number. The discovery, however, that alternative gene splicing and transcription are widespread phenome...

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Detalhes bibliográficos
Main Authors: Parra, Genís, Reymond, Alexandre, Dabbouseh, Noura, Dermitzakis, Emmanouil T., Castelo, Robert, Thomson, Timothy M., Antonarakis, Stylianos E., Guigó, Roderic
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356127/
https://ncbi.nlm.nih.gov/pubmed/16344564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.4145906
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