Precipitous Release of Methyl-CpG Binding Protein 2 and Histone Deacetylase 1 from the Methylated Human Multidrug Resistance Gene (MDR1) on Activation

Overexpression of the human multidrug resistance gene 1 (MDR1) is a negative prognostic factor in leukemia. Despite intense efforts to characterize the gene at the molecular level, little is known about the genetic events that switch on gene expression in P-glycoprotein-negative cells. Recent studie...

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Autors principals: El-Osta, Assam, Kantharidis, Phillip, Zalcberg, John R., Wolffe, Alan P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
Matèries:
Transcriptional Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC135609/
https://ncbi.nlm.nih.gov/pubmed/11865062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.6.1844-1857.2002
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