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Precipitous Release of Methyl-CpG Binding Protein 2 and Histone Deacetylase 1 from the Methylated Human Multidrug Resistance Gene (MDR1) on Activation

Overexpression of the human multidrug resistance gene 1 (MDR1) is a negative prognostic factor in leukemia. Despite intense efforts to characterize the gene at the molecular level, little is known about the genetic events that switch on gene expression in P-glycoprotein-negative cells. Recent studie...

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Udgivet i:Mol Cell Biol
Principais autores: El-Osta, Assam, Kantharidis, Phillip, Zalcberg, John R., Wolffe, Alan P.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2002
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135609/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11865062/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.6.1844-1857.2002
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