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Competitive Cofactor Recruitment by Orphan Receptor Hepatocyte Nuclear Factor 4α1: Modulation by the F Domain

For most ligand-dependent nuclear receptors, the status of endogenous ligand modulates the relative affinities for corepressor and coactivator complexes. It is less clear what parameters modulate the switch between corepressor and coactivator for the orphan receptors. Our previous work demonstrated...

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Autori principali: Ruse, Michael D., Privalsky, Martin L., Sladek, Frances M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC135595/
https://ncbi.nlm.nih.gov/pubmed/11865043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.6.1626-1638.2002
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