The Cysteine Desulfurase IscS Is Required for Synthesis of All Five Thiolated Nucleosides Present in tRNA from Salmonella enterica Serovar Typhimurium

Deficiency of a modified nucleoside in tRNA often mediates suppression of +1 frameshift mutations. In Salmonella enterica serovar Typhimurium strain TR970 (hisC3737), which requires histidine for growth, a potential +1 frameshifting site, CCC-CAA-UAA, exists within the frameshifting window created b...

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Bibliographische Detailangaben
Hauptverfasser: Nilsson, Kristina, Lundgren, Hans K., Hagervall, Tord G., Björk, Glenn R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Physiology and Metabolism
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC135462/
https://ncbi.nlm.nih.gov/pubmed/12446633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.24.6830-6835.2002
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