The Cysteine Desulfurase IscS Is Required for Synthesis of All Five Thiolated Nucleosides Present in tRNA from Salmonella enterica Serovar Typhimurium

Deficiency of a modified nucleoside in tRNA often mediates suppression of +1 frameshift mutations. In Salmonella enterica serovar Typhimurium strain TR970 (hisC3737), which requires histidine for growth, a potential +1 frameshifting site, CCC-CAA-UAA, exists within the frameshifting window created b...

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Bibliographic Details

Published in:	J Bacteriol
Main Authors:	Nilsson, Kristina, Lundgren, Hans K., Hagervall, Tord G., Björk, Glenn R.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2002
Subjects:	Physiology and Metabolism
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135462/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12446633/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.184.24.6830-6835.2002
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