The rpoZ Gene, Encoding the RNA Polymerase Omega Subunit, Is Required for Antibiotic Production and Morphological Differentiation in Streptomyces kasugaensis

The occurrence of pleiotropic mutants that are defective in both antibiotic production and aerial mycelium formation is peculiar to streptomycetes. Pleiotropic mutant KSB was isolated from wild-type Streptomyces kasugaensis A1R6, which produces kasugamycin, an antifungal aminoglycoside antibiotic. A...

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Detalhes bibliográficos
Main Authors: Kojima, Ikuo, Kasuga, Kano, Kobayashi, Masayuki, Fukasawa, Akira, Mizuno, Satoshi, Arisawa, Akira, Akagawa, Hisayoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Genetics and Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC135429/
https://ncbi.nlm.nih.gov/pubmed/12426327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.23.6417-6423.2002
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