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The rpoZ Gene, Encoding the RNA Polymerase Omega Subunit, Is Required for Antibiotic Production and Morphological Differentiation in Streptomyces kasugaensis

The occurrence of pleiotropic mutants that are defective in both antibiotic production and aerial mycelium formation is peculiar to streptomycetes. Pleiotropic mutant KSB was isolated from wild-type Streptomyces kasugaensis A1R6, which produces kasugamycin, an antifungal aminoglycoside antibiotic. A...

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Bibliografiske detaljer
Main Authors: Kojima, Ikuo, Kasuga, Kano, Kobayashi, Masayuki, Fukasawa, Akira, Mizuno, Satoshi, Arisawa, Akira, Akagawa, Hisayoshi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC135429/
https://ncbi.nlm.nih.gov/pubmed/12426327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.23.6417-6423.2002
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