Short-Sequence Tandem and Nontandem DNA Repeats and Endogenous Hydrogen Peroxide Production Contribute to Genetic Instability of Streptococcus pneumoniae

Loss-of-function mutations in the following seven pneumococcal genes were detected and analyzed: pspA, spxB, xba, licD2, lytA, nanA, and atpC. Factors associated with these mutations included (i) frameshifts caused by reversible gain and loss of single bases within homopolymeric repeats as short as...

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Bibliografiske detaljer

Udgivet i:	J Bacteriol
Principais autores:	Pericone, Christopher D., Bae, Deborah, Shchepetov, Mikhail, McCool, Tera, Weiser, Jeffrey N.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2002
Fag:	Genetics and Molecular Biology
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135236/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12142409/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.184.16.4392-4399.2002
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