Characterization of Symmetric Complexes of Nerve Growth Factor and the Ectodomain of the Pan-neurotrophin Receptor, p75(NTR)

Nerve growth factor (NGF) is the ligand for two unrelated cellular receptors, TrkA and p75(NTR), and acts as a mediator in the development and maintenance of the mammalian nervous system. Signaling through TrkA kinase domains promotes neuronal survival, whereas activation of the p75(NTR) “death doma...

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Hlavní autoři: Aurikko, Jukka P., Ruotolo, Brandon T., Grossmann, J. Günter, Moncrieffe, Martin C., Stephens, Elaine, Leppänen||, Veli-Matti, Robinson, Carol V., Saarma||, Mart, Bradshaw, Ralph A., Blundell, Tom L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1352310/
https://ncbi.nlm.nih.gov/pubmed/16009712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M503189200
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