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Phage TP901-1 Site-Specific Integrase Functions in Human Cells

We demonstrate that the site-specific integrase encoded by phage TP901-1 of Lactococcus lactis subsp. cremoris has potential as a tool for engineering mammalian genomes. We constructed vectors that express this integrase in Escherichia coli and in mammalian cells and developed a simple plasmid assay...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Bacteriol
Hauptverfasser: Stoll, Stephanie M., Ginsburg, Daniel S., Calos, Michele P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2002
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135144/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12057961/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.184.13.3657-3663.2002
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