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Lecithin-retinol Acyltransferase Is Essential for Accumulation of All-trans-Retinyl Esters in the Eye and in the Liver

Lecithin-retinol acyltransferase (LRAT), an enzyme present mainly in the retinal pigmented epithelial cells and liver, converts all-trans-retinol into all-trans-retinyl esters. In the retinal pigmented epithelium, LRAT plays a key role in the retinoid cycle, a two-cell recycling system that replenis...

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Hlavní autoři: Batten, Matthew L., Imanishi, Yoshikazu, Maeda, Tadao, Tu, Daniel C., Moise, Alexander R., Bronson, Darin, Possin, Daniel, Van Gelder, Russell N., Baehr, Wolfgang, Palczewski, Krzysztof
Médium: Artigo
Jazyk:Inglês
Vydáno: 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1351249/
https://ncbi.nlm.nih.gov/pubmed/14684738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M312410200
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